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KPV
α-MSH C-terminal tripeptide — anti-inflammatory research.
- Lys-Pro-Val tripeptide
- Mucosal & gut research
- 10 mg vial
⚠ For research purposes only · Not for human consumption
About KPV
KPV (Lysine-Proline-Valine) is the three-residue C-terminal fragment of α-melanocyte-stimulating hormone. By isolating this minimal sequence, researchers obtained a peptide that retains the anti-inflammatory profile of α-MSH while losing the melanocortin receptor activity responsible for pigmentation. KPV has become a reference tool in studies of inflammatory bowel models, mucosal barrier integrity and dermal inflammation, where it is reported to downregulate NF-κB signaling and pro-inflammatory cytokine production. Each 10 mg vial is lyophilized at ≥99% HPLC purity, sealed under nitrogen and shipped with a full Certificate of Analysis.
Mechanism of action
Acts intracellularly to inhibit NF-κB activation and downstream cytokine release, independent of melanocortin receptors.
Specifications
Independently tested · Certificate of Analysis on request
| Parameter | Value |
|---|---|
| Sequence purity | ≥ 99% (HPLC) |
| Dosage | 10 mg vial |
| Form | Lyophilized powder |
| Storage | −20°C |
Shipping & delivery
Free shipping over $250Free shipping over $250
Orders of $250 or more ship free worldwide. Below the threshold, a flat research-logistics fee is calculated at checkout based on destination and cold-chain requirements.
Cold-chain & packaging
Temperature-sensitive compounds ship in insulated containers with phase-change gel packs and a temperature-monitor strip. Lyophilized peptides are double-sealed in tamper-evident packaging with desiccant.
Processing & transit
Orders are processed within 24–48 business hours. Domestic delivery: 2–4 business days. International express: 3–7 business days, with full tracking and signature on receipt.
We ship globally to verified research institutions and qualified labs. Customers are responsible for any local import duties or taxes. Cold-chain shipments are dispatched Monday–Wednesday to avoid weekend transit delays.



