Free shipping on orders over $250 · For research purposes only
KPV

Recovery & Repair

KPV

α-MSH C-terminal tripeptide — anti-inflammatory research.

4.6· 124 reviews
$65.00 – $85.00
  • Lys-Pro-Val tripeptide
  • Mucosal & gut research
  • 10 mg vial
1

⚠ For research purposes only · Not for human consumption

Free shipping $250+
Lot-traceable COA
≥99% HPLC

About KPV

KPV (Lysine-Proline-Valine) is the three-residue C-terminal fragment of α-melanocyte-stimulating hormone. By isolating this minimal sequence, researchers obtained a peptide that retains the anti-inflammatory profile of α-MSH while losing the melanocortin receptor activity responsible for pigmentation. KPV has become a reference tool in studies of inflammatory bowel models, mucosal barrier integrity and dermal inflammation, where it is reported to downregulate NF-κB signaling and pro-inflammatory cytokine production. Each 10 mg vial is lyophilized at ≥99% HPLC purity, sealed under nitrogen and shipped with a full Certificate of Analysis.

Mechanism of action

Acts intracellularly to inhibit NF-κB activation and downstream cytokine release, independent of melanocortin receptors.

Specifications

Independently tested · Certificate of Analysis on request

ParameterValue
Sequence purity≥ 99% (HPLC)
Dosage10 mg vial
FormLyophilized powder
Storage−20°C

Shipping & delivery

Free shipping over $250

Orders of $250 or more ship free worldwide. Below the threshold, a flat research-logistics fee is calculated at checkout based on destination and cold-chain requirements.

Cold-chain & packaging

Temperature-sensitive compounds ship in insulated containers with phase-change gel packs and a temperature-monitor strip. Lyophilized peptides are double-sealed in tamper-evident packaging with desiccant.

Processing & transit

Orders are processed within 24–48 business hours. Domestic delivery: 2–4 business days. International express: 3–7 business days, with full tracking and signature on receipt.

We ship globally to verified research institutions and qualified labs. Customers are responsible for any local import duties or taxes. Cold-chain shipments are dispatched Monday–Wednesday to avoid weekend transit delays.

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